glutathione s transferase theta 2 antibody Human Glutathione S Transferase theta 2 Antibody - glutathione-peroxidase-test Glutathione S Transferase Theta 2 Unveiling the Precision of Glutathione S Transferase Theta 2 Antibody

noom-vs-hers-semaglutide The glutathione s transferase theta 2 antibody is a vital tool for researchers investigating the intricate roles of the glutathione S-transferase (GST) family of proteins. This specific antibody targets Glutathione S transferase theta 2 (GSTT2), a key enzyme that plays a crucial role in cellular detoxification by catalyzing the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compoundsGlutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugationof reduced glutathione to a variety .... Understanding the expression and function of GSTT2 is paramount across diverse biological and medical research areas, including cancer immunotherapy, cardiovascular disease, and general cellular defense mechanisms.Listed below areanti-Glutathione-S-transferase antibodiesfrom multiple suppliers. Glutathione-S-transferase is a reported alias name for the human gene HPGDS.

The Significance of Glutathione S-Transferases in Cellular Health

Glutathione S-transferases (GSTs) are a superfamily of enzymes renowned for their involvement in both endogenous and xenobiotic metabolism. This diverse group is further categorized into eight distinct families, including alpha, kappa, mu, omega, pi, sigma, theta, and zeta. The theta class, to which GSTT2 belongs, is particularly noteworthy. Recent research, such as findings on the "The role of glutathione S-transferases in human disease pathogenesis" and "The Multifaceted Role of Glutathione S-Transferases in Health and Disease," underscores their broad impact. Notably, studies have linked genetic variations, such as the glutathione S-transferase theta-null genotype, to increased cardiovascular morbidity and mortality in conditions like type 2 diabetes.

The functionality of GSTT2 stems from its enzymatic activityRat Gstt2(Glutathione S-transferase theta-2) ELISA Kit. It facilitates the attachment of glutathione to potentially harmful molecules, rendering them more water-soluble and thus easier for the body to excrete. This process is fundamental to protecting cells from oxidative stress and damage caused by a wide array of toxins, carcinogens, and metabolic byproducts.The role of glutathione S-transferases in human disease ...

Applications and Characterization of Glutathione S Transferase Theta 2 Antibodies

The development and validation of glutathione s transferase theta 2 antibodies have opened significant avenues for research. These antibodies are essential for detecting and quantifying GSTT2 protein levels in various biological samples. Researchers can utilize these reagents for a range of applications, including:

* Western Blotting (WB): To determine the molecular weight and relative abundance of GSTT2 in cell or tissue lysates. Several product descriptions highlight their suitability for WB, with specific bands appearing around 27Human Glutathione S-Transferase Theta 2.3 kDa for the human recombinant protein.

* Immunohistochemistry (IHC) and Immunocytochemistry (ICC)/Immunofluorescence (IF): To visualize the cellular and subcellular localization of GSTT2, providing insights into its tissue-specific expression patterns and cellular roles. For instance, one description notes expression at low levels in liver, and in lung, it is found in ciliated bronchiolar cells, alveolar macrophages, and alveolar type II cells.

* Enzyme-Linked Immunosorbent Assay (ELISA): For quantitative analysis of GSTT2 in biological fluids or extracts. Specific kits, such as the Human GSTθ2/GSTt2 CLIA Kit, are available for precise measurements.GSTT2B antibody (17622-1-AP)

* Flow Cytometry (FC): To analyze GSTT2 expression on a single-cell level, particularly useful in immune cell studies.

These antibodies are often characterized by their specificity, isotype (commonly IgG), and the host animal from which they were raised (eRecombinant Human Glutathione S-transferase theta-2B ....g., rabbit polyclonal antibody to GSTT2, mouse monoclonal antibody). For example, the Boster Bio GSTT2 (Glutathione S Transferase Theta 2) mouse monoclonal antibody, clone OTI3B6 (formerly 3B6), is cited as being tested in FC, IF, IHC, WB. Similarly, rabbit anti-Mouse, Rat Glutathione S Transferase Theta 2 antibodies are prepared "against GSTt2." Some products are also validated for reactivity with specific species, including human, mouse, and rat.

Specific Antibody Offerings and Features

A wide array of glutathione s transferase theta 2 antibodies are commercially available, catering to diverse research needs.Structure, function and evolution of glutathione transferases - PMC - NIH These include:

* Polyclonal Antibodies: Often raised in rabbits, these antibodies recognize multiple epitopes on the GSTT2 protein. Examples include rabbit polyclonal antibody to GSTT2 and polyclonal antibody preparation offerings.

* Monoclonal Antibodies: Produced from a single clone of B cells, these offer high specificity and consistency. Examples include the Glutathione S Transferase theta 2 (GSTT2) Mouse Monoclonal Antibody, clone OTI4F9 (formerly 4F9), and the GSTT2 (Glutathione S Transferase theta 2) mouse monoclonal antibody.

* Recombinant Antibodies: These are produced using recombinant DNA technology, ensuring batch-to-batch consistency and high purity. Recombinant Human Glutathione S-transferase theta-2B and Recombinant Mouse Glutathione S Transferase Theta 2 (GSTt2) are examples of such products.

Key features to consider when selecting a glutathione s transferase theta 2 antibody include the purification method (e.Structure, function and evolution of glutathione transferases - PMC - NIHg., purified by antigen affinity column chromatography), the format (e.g., lyophilized or liquid), concentration (e.g., 0.5mg/ml), and storage recommendations (typically +4C for frequent use). Some antibodies are also available in different sizes, such as Full Size and Trial Size, to accommodate varying experimental scales.

GSTT2 and its Related Family Members

The focus on GSTT2 extends to its broader family. The GSTT2B antibody, for instance, targets a related isoformStructure, function and evolution of glutathione transferases - PMC - NIH. Understanding the distinctions and overlaps between different glutathione S-transferase families, such as GSTM2 (Glutathione S-Transferase Mu2), is crucial for comprehensive research. The identification of GSTT2 as a member of the glutathione s-transferase (GST) family of proteins, which encompasses eight distinct classes, highlights the complexity and importance of this enzyme group.

In summary, the glutathione s transferase theta 2 antibody is an indispensable reagent for researchers delving into cellular detoxification, disease mechanisms, and therapeutic interventionsGlutathione S Transferase Theta 2 (GSTT2) Antibody. Its availability in various formats and its proven utility in techniques such as Western Blotting and Immunohistochemistry enable detailed investigations into the multifaceted roles of GSTT2 and its contribution to maintaining cellular homeostasis and overall health. The ongoing exploration into glutathione s transferase functions continues to reveal their profound impact on human well-being.